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Product Manager Jad Ather raised the risk of foodborne disease to some consumers in California in order to maintain food safety. Previously he worked at Bose, where he was director of product marketing for audio. Read More
Kristina Ash wrote a post for the New York Times’s Room for Debate explaining why software developers should keep an open mind when it comes to the gender gap in tech. Read More
The New York Review of Books has an essay by the award-winning essayist and novelist Thomas McGuane on Russia, Trump and the media; the “last wall”; Russia’s economy; Russia’s social and intellectual collapse; and what it’s like to be a Russian in the U.S. and vice versa.Kinetic proofreading.
The kinetics of a protein synthesis mechanism, based on the kinetic proofreading model of Frank and Ferrell (FE-model), was studied. The kinetic proofreading (KP) scheme for amino acid incorporation is based on the fact that the ribosome is sensitive to the aminoacyl tRNA and in normal peptide elongation reactions the ribosome is capable of rejecting the peptide extension in favor of a complete translocation. We investigated the performance of the KP model in a realistic 3-step elongation scheme. All three steps were treated separately in the study. The net elongation rate was found to be 0.78 x 10(6) s(-1) with an overall rate constant for the entire system of 1.04 x 10(6) s(-1). Using a minimum overall elongation constant of 3 x 10(6) s(-1), we obtained an effective rate constant for the third elongation step of 1.7 x 10(6) s(-1) which is surprisingly