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An alternative method of grading embryo development was used to investigate the extent to which suboptimal fertilization is related to low embryo quality. The method uses the ability of human oocytes to reach the 8-cell stage in culture. The fertilization rate and cleavage of oocytes from these 10 couples were compared with their embryo development at day 3, day 5, and day 6 of culture. A subset of these embryos has been kept for the assessment of blastocyst development. The fertilization rate was 53.0% and was lower in couples with lower oocyte quality. The rate of cleavage improved with increasing embryo age, but overall was not related to embryo quality. The cleavage rate was related to the fertilization rate and higher in embryos which developed blastocysts in vitro. The method of grading embryo development has proved its accuracy in identifying embryos at greatest risk of development to the blastocyst stage. This may be of value in oocyte donation programs which have a choice between creating blastocysts in vitro or in vivo.Every hour of every day, the globe’s economic power centers are making plans to exploit whatever new energy source they find most appealing. The only constant in the evolving picture is that, as always, the best bets for maximum returns are where the geologists say the most oil and gas are likely to be found.
When West Texas Intermediate’s price peaked in July 2014, the Houston office of SandRidge Energy (I:SAN) was preparing to double the company’s acreage in the Permian Basin — where the world’s best oil and gas resources lie under a layer of sandstone.
The company was focused on drilling, using state-of-the-art, high-pressure horizontal wells that produce upward of 60,000 barrels per day.
“You’re seeing the well count increase,” SandRidge’s executive vice president of exploration Chris Skrebowski told us at the time. “There’s no slowdown. There are a number of companies that are doing well, and they’re drilling and they’